Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3331573 | Hematology/Oncology Clinics of North America | 2008 | 13 Pages |
Abstract
Antiphospholipid antibodies are essential in the diagnosis of antiphospholipid syndrome (APS), or the classic “Hughes syndrome,” which is a systemic disorder that is autoimmune in nature. They are also found in various infections in low titers without any evidence of thrombotic manifestations of APS. However, in a few infections, when antiphospholipid antibodies are associated with protein cofactor, there can be associated thrombosis. Different infections are also responsible for triggering a subset of lethal APS, acute catastrophic APS. This situation requires prompt diagnosis and aggressive treatment of the infection to prevent severe complications.
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Authors
Navin M. Amin,