Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3331936 | Hematology/Oncology Clinics of North America | 2009 | 12 Pages |
Abstract
Acquired severe aplastic anemia can be treated successfully with either immunosuppressive therapy or bone marrow transplantation. Although immunosuppressive therapy can be readily administered to all patients, it is not a curative approach and is associated with a higher risk of clonal evolution than is transplantation, which yields rapid and long-lasting hematologic remission. This article reviews the key diagnostic and prognostic factors that influence the choice of therapy in patients with acquired aplastic anemia.
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Authors
Andrea Bacigalupo, Jakob Passweg,