Article ID Journal Published Year Pages File Type
3332160 Hematology/Oncology Clinics of North America 2007 13 Pages PDF
Abstract
Cardiovascular disease is prevalent in our medical and surgical. Patients who have atherosclerotic heart disease suffer from endothelial disorders that predispose them to plaque and thrombus formation in diseased arteries. As our knowledge of platelet physiology improves, we can understand the contribution of platelet activation to arterial disease and we can specifically inhibit that activation with platelet-inhibitory drugs. The recent increase in the number of coronary interventional procedures performed has spawned the increasing use of antiplatelet medication as prophylaxis against thrombus formation in the instrumented artery.
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