Article ID Journal Published Year Pages File Type
3332181 Hematology/Oncology Clinics of North America 2008 13 Pages PDF
Abstract

Constitutional (hereditary) genetic variation and somatic genetic alterations acquired during transformation to the neoplastic phenotype are both critical determinants of cancer outcome, and can ultimately have a significant effect on cancer survivorship. This article discusses the role of constitutional and somatic genetics in determining outcome and survivorship following a diagnosis of cancer using illustrative examples primarily from the hematologic malignancies.

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Health Sciences Medicine and Dentistry Hematology
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