| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3332605 | HIV & AIDS Review | 2007 | 5 Pages |
SummaryThe aim of the study was to assess the validity of the IVth generation tests in the screening diagnosis of HIV infection among sperm donors and women undergoing facilitated fertilization. The studied group included 1000 volunteers who underwent voluntary HIV infection tests. Among the studied subjects there were 531 men-sperm donors and 469 women prepared for the process of artificial insemination. The negative results of the screening VIDAS HIV DUO and VIDAS HIV DUO QUICK tests were observed in 983 cases. Positive results were reported in 9 subjects (3 women and 6 men) in VIDAS HIV DUO test and in 8 subjects (2 women and 6 men) in VIDAS HIV DUO QUICK test. The specificity of the VIDAS HIV DUO test was 98,5%. This test has been replaced by the VIDAS HIV DUO QUICK test, with a specificity of 99,3%. In assessing the validity of the test, 100% negative predictive value and a low positive predictive value – 33,3% for VIDAS HIV DUO test and 50% for VIDAS HIV DUO QUICK test was observed. False positive results were observed in 10 subjects (1%) studied. The VIDAS HIV DUO QUICK test has a high sensitivity and fairly good specificity. Reduced time of performance and full automatization assuring the safety of medical staff strongly influence the recommendation for its daily use in medical practice. HIV infection incidence among sperm donors and women who undergo aided reproduction is not high but single positive cases require complex diagnosis of this population.
