| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3333768 | Seminars in Hematology | 2010 | 9 Pages |
Abstract
Allogeneic hematopoietic stem cell transplantation (HSCT) is the only potential cure for most bone marrow (BM) failure syndromes and hemoglobinopathies. Over the past decade, umbilical cord blood (UCB) has been used more frequently as a stem cell source in patients who lack a suitable BM donor. Although graft failure remains a significant problem, UCB transplantation (UCBT) using the optimal conditioning regimen can be a salvage treatment for patients without a suitable BM donor and warrants evaluation in further prospective studies.
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Authors
Margaret L. MacMillan, Mark C. Walters, Eliane Gluckman,