| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3333946 | Seminars in Hematology | 2009 | 8 Pages |
Abstract
Numerous genetic abnormalities have been identified in acute lymphoblastic leukemia (ALL). Here we review the recurrent abnormalities with emphasis on those recently discovered, and discuss their association with chemotherapy resistance or sensitivity and with clinical response to therapy. Also, the role of genetic abnormalities in leukemogenesis and their potential as therapeutic targets will be discussed.
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Authors
Jules P.P. Meijerink, Monique L. den Boer, Rob Pieters,