Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3334754 | Surgical Pathology Clinics | 2010 | 34 Pages |
Abstract
Lymph node-based peripheral T-cell lymphomas are rare and exhibit a morphologic spectrum that overlaps with reactive lymphoid hyperplasia, B-cell lymphomas, and Hodgkin lymphoma, presenting a diagnostic challenge. This review focuses on the major categories of lymph node-based peripheral T-cell lymphomas recognized by the 2008 World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Diagnostic strategies for approaching T-cell neoplasms using a combined clinical, morphologic, immunophenotypic, and genetic approach are presented. Practical information to aid in distinguishing peripheral T-cell lymphomas from other hematologic malignancies and benign conditions is provided.
Related Topics
Health Sciences
Medicine and Dentistry
Hematology
Authors
Matthew MD, Ahmet MD, PhD,