Article ID Journal Published Year Pages File Type
3334995 Transfusion and Apheresis Science 2014 10 Pages PDF
Abstract

The objectives of this study were to evaluate the cost-effectiveness and budget impact of octaplasLG® compared with fresh-frozen plasma (FFP) in all patients receiving a transfusion in Canada. A decision analytic framework was used to model acute and long-term complications that could follow plasma transfusion. Over a life time horizon, the cost with octaplasLG® were CA$612.91, which is CA$303.14 less than those with FFP. OctaplasLG® resulted in 0.021 quality adjusted life years (QALYs) gained in comparison with FFP. Because of higher efficacy and lower costs, octaplasLG® is expected to be the dominant treatment option over FFP in Canada.

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