| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3335154 | Transfusion and Apheresis Science | 2013 | 5 Pages |
AimThe present study was planned to determine the effects of regular exercise program on hematopoietic stem cell (HSC) mobilization prior to autologous stem cell transplantation.MethodTwenty-two consecutive patients were enrolled in the study. A regular 20 min exercise program was administered to the patients. The hematopoietic stem cell mobilization outcome, number of Granulocyte Colony-Stimulating Factor (G-CSF) and aphaeresis application days were compared with 20 case-matched controls who did not receive exercise program during HSC mobilization.ResultsThe median number of CD34+ stem cells collected in the exercise and control groups were 8.15 × 106/kg (range: 2.85–33.06 × 106/kg) and 7.3 × 106/kg (range: 1.78–25.9 × 106/kg), respectively (p = 0.696). G-CSF was administered for a median of 8 days (range, 5–10) in the exercise group and 8 days (range, 5–12) in the control group (p = 0.848). The median apheresis duration was 1 day (range, 1–3) in both exercise and control groups (p = 0.226).ConclusionExercise seems to have a positive impact on stem cell mobilization though without statistical significance.
