Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3335706 | Transfusion and Apheresis Science | 2012 | 6 Pages |
Abstract
Patients undergoing peripheral blood stem cell (PBSC) collection for autologous transplantation may have a greater incidence of thrombosis due to a number of risk factors (RFs). These factors may be related to the patient himself (history of thromboembolism, tumour type and stage, treatment), to the procedure and/or to the mobilizing agents used. In our study of 97 patients, 32 were considered high risk (HR) patients and were therefore treated with a low prophylactic dose of enoxaparin the evening before stem cell apheresis. Neither thrombotic nor hemorrhagic complications were observed, even though pre-apheresis platelet levels were below 50 × 109 l−1 in 19 procedures.
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Authors
Patrizia Politi, Suzy M.T. Durazzi, Francesco Picardi,