| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3335805 | Transfusion and Apheresis Science | 2010 | 6 Pages |
Abstract
Anti-PP1Pk is a rare, biphasic antibody with the ability to cause immediate hemolytic transfusion reactions and early spontaneous abortions. The antibody is formed by individuals with the p phenotype. A blood donor with anti-PP1Pk and the p phenotype was identified through routine donor screening. A sister was found to also be p phenotype. At that time, the sister was 24 weeks pregnant. Subsequently, the original blood donor became pregnant. Both individuals were followed throughout their pregnancies and delivered infants without complications from anti-PP1Pk antibodies. The literature regarding anti-PP1Pk, the p phenotype, and recurrent pregnancy loss in this setting is reviewed.
Related Topics
Health Sciences
Medicine and Dentistry
Hematology
Authors
Georgette R. Benidt, Elizabeth A. Jaben, Jeffrey L. Winters, James R. Stubbs,