Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3336211 | Transfusion and Apheresis Science | 2007 | 7 Pages |
Abstract
We compared cryopreservation of peripheral blood progenitor cell (PBPC) products immediately and after overnight storage. There was no statistically significant difference in the groups regarding median CD34+CD34+ cell count of the product, storage duration at −80 °C, viability rates, neutrophil and platelet engraftment days. Overnight storage of products with leukocyte count >300 × 109/l has longer leukocyte (P = 0.03) and platelet (P = 0.01) engraftment days compared to other groups. Overnight storage without adding any medium or plasma for the apheresis product with leukocyte count of less than 300 × 109/l in a commercially available refrigerator can easily and safely be used in transplantation centers.
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Authors
Ayhan Donmez, Seckin Cagirgan, Guray Saydam, Murat Tombuloglu,