Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3336320 | Transfusion and Apheresis Science | 2006 | 5 Pages |
Abstract
Anti-KEL7 (anti-Jsb) is a rare antibody that has been related to haemolytic transfusion reactions and HDN. We report a case of anti-KEL7 alloimmunization detected in a pregnant woman who had an obstetric previous history of four miscarriages and one stillborn. Employing classical immunohematological techniques, we studied the propositus and her available relatives. Due to the unavailability of commercial anti-KEL6 and anti-KEL7 reagents, we used a KEL∗6,7 genotyping method as an alternative tool to contribute with the identification of the alloantibody origin. The results of KEL genotyping showed that the propositus was KEL∗6/6 homozygous, while her second partner was KEL∗7/7 homozygous.
Keywords
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Hematology
Authors
Edmir Boturão-Neto, Akemi Kuroda Chiba, Melca Maria Oliveira Barros, Adriana Barretto de Mello, Antonio Fabron Jr., José Orlando Bordin,