Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
333729 | Psychiatry Research | 2011 | 5 Pages |
Abstract
The authors studied the prevalence of the human leukocyte antigen (HLA) Class I gene in 136 (85 male, 51 female) India-born schizophrenia patients residing in and around the Siliguri subdivision of West Bengal by the PCR-SSP method. The control group consisted of 150 age- and sex-matched healthy individuals from the same ethnic group as the patients. Increased frequency of HLA A*03 as well as decreased frequencies of HLA A*31 and HLA B*51, was noted. The study suggests the possible existence of a susceptibility locus for schizophrenia within the HLA region.
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Authors
Bisu Singh, Nirmal Kumar Bera, Santanu De, Chittaranjan Nayak, Tapas Kumar Chaudhuri,