HCV infection during renal replacement therapy: What we have learnt in two decade?

HCV infection is most common hepatotropic blood borne infection in hemodialysis unit and prevalent differently in different units. It causes not only mortality but significant morbidity and difficulty in management of such cases. Prevention is better than treatment of such cases. In addition to following universal precaution, there is role of isolation of these patients to restrict spread of infection. If patient can afford, these patients should be treated with interferon (preferably pegylated) with/without ribavirin, whether patient is for renal transplant or not. Treatment prevent complication during maintenance hemodialysis and also following renal transplantation.