| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3341730 | Autoimmunity Reviews | 2013 | 6 Pages |
Abstract
Common variable immunodeficiency is a collection of diseases characterized by primary hypogammaglobulinemia. The causes of CVID are extremely heterogeneous and may affect virtually every pathway linked to B cell development and function. Clinical manifestations of CVID mainly include recurrent bacterial infections, but autoimmune, gastrointestinal, lymphoproliferative, granulomatous, and malignant disorders have also been frequently reported as associated conditions. We aimed to focus on the state of the art of the relationship between infections, inflammation and autoimmunity in CVID.
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Authors
Simone Baldovino, Davide Montin, Silvana Martino, Savino Sciascia, Elisa Menegatti, Dario Roccatello,