Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3343653 | Best Practice & Research Clinical Rheumatology | 2006 | 7 Pages |
Abstract
This chapter reviews evidence from family and twin studies supporting the strong genetic predisposition of the spondyloarthritides (SpA), which is only partially attributable to the major histocompatibility locus. The current concept of SpA heterogeneity has been challenged by family studies which showed that all articular and extra-articular manifestations were linked together, and most likely to the same genetic factors.
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Authors
Maxime Breban,