Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3346074 | Current Opinion in Immunology | 2011 | 6 Pages |
Abstract
Atopic dermatitis (AD) results from barrier defects combined with modified immune responses of the innate and the adaptive immune system to exogenous and endogenous factors. Recent research has continued to sort out the complex pathophysiologic puzzle of this frequent skin disease. However, the network of mechanisms leading to the manifestation of AD is far from being completely understood.
► Atopic dermatitis is the most common inflammatory skin disease in the general population. ► Atopic dermatitis is a genetic disease triggered by infection, allergens and stress. ► Atopic dermatitis results from barrier defects combined with abnormal innate and adaptive immune responses.
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Authors
Natalija Novak, Donald YM Leung,