Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3346138 | Current Opinion in Immunology | 2009 | 8 Pages |
Abstract
The logistic problem of B cell antigen encounter in the lymph node has recently been studied by dynamic imaging using two-photon microscopy. These studies combined with the early studies of antigen transport have yielded a more complete picture of the orchestration of B cell activation in vivo. Here we summarize the recent advances and focus on the specialized macrophages that are critical to this process and the role of B cells themselves as antigen transporting cells.
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Authors
Tri Giang Phan, Elizabeth E Gray, Jason G Cyster,