| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 334621 | Psychiatry Research: Neuroimaging | 2008 | 4 Pages |
Abstract
The medial temporal cortex (MTC) has been implicated in the pathogenesis of pediatric major depressive disorder (MDD). Eleven MDD case-control pairs underwent proton magnetic resonance spectroscopic imaging. N-acetyl-aspartate was lower in the left MTC (27%) in MDD patients versus controls. Lower N-acetyl-aspartate concentrations in MDD patients may reflect reduced neuronal viability.
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Authors
Frank P. MacMaster, Gregory J. Moore, Aileen Russell, Yousha Mirza, S. Preeya Taormina, Christian Buhagiar, David R. Rosenberg,