Article ID Journal Published Year Pages File Type
334756 Psychiatry Research: Neuroimaging 2014 4 Pages PDF
Abstract

•Familial patterns of forethought, a prospective function of working memory, were explored in children ADHD and their parents.•Cerebral activation during fMRI was compared in ADHD parent–child dyads vs. control parent–child dyads.•Reduced activations in ADHD dyads were found in inferior frontal gyrus, right superior parietal lobule and left inferior parietal lobule, suggesting that fronto-parietal abnormalities characterize ADHD families.

There are only a few published reports of neural abnormalities within the families of children with attention deficit/hyperactivity disorder (ADHD). Functional magnetic resonance imaging was used to compare cerebral activation of ADHD and control biological parent–child dyads during forethought, a prospective function of working memory. Reduced activations in ADHD dyads were found in the inferior frontal gyrus, right superior parietal lobule and left inferior parietal lobule. This suggests that fronto-parietal abnormalities are shared within ADHD families.

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