Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3348041 | Diagnostic Microbiology and Infectious Disease | 2009 | 6 Pages |
Abstract
We report on the underlying molecular mechanisms likely responsible for the high-level fluconazole resistance in a Candida lusitaniae clinical isolate. Fluconazole resistance correlated with overexpression of ERG11 and of several efflux pump genes, in particular, the orthologs of the Candida albicans MDR1, PDR16, CDR1, CDR2, and YOR1.
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Authors
David Reboutier, Mathieu Piednoël, Stéphanie Boisnard, Audrey Conti, Virginie Chevalier, Martine Florent, Stéphanie Gibot-Leclerc, Bruno Da Silva, Christiane Chastin, Karim Fallague, Anne Favel, Thierry Noël, Gwenaël Ruprich-Robert,