Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3348062 | Diagnostic Microbiology and Infectious Disease | 2010 | 5 Pages |
Abstract
We investigated the prevalence and epidemiology of AmpC plasmidic cephalosporinases in Escherichia coli clinical strains resistant to third-generation cephalosporins during a 5-year period at Nantes University Hospital, France (3100 beds). The prevalence and diversity of plasmidic cephalosporinase did not increase during the study period (0.09% of 25 861 E. coli isolates); only CMY-2 producers were detected (and 1 new variant, with a Y-to-C substitution at position 219). CMY-2–producing strains belonged to the 4 main phylogenetic groups and to 11 different sequence types. Three sequence types included more than 1 isolate (ST156, ST46, and ST354).
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Authors
Stéphane Corvec, Lise Crémet, Céline Leprince, Sandie Dauvergne, Alain Reynaud, Didier Lepelletier, Nathalie Caroff,