Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3350464 | Human Immunology | 2014 | 4 Pages |
Abstract
The role of donor HLA-DP-specific antibodies after renal transplantation is controversial, and only preformed HLA-DP-specific antibodies have been shown to mediate rejection. Here we present a case of late humoral rejection mediated by de novo donor HLA-DP-specific antibodies in a non-sensitized recipient. This unique case demonstrates the pathogenic role of de novo anti-DP antibodies and suggests that HLA-DP matching might be relevant for renal transplantation.
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Authors
Pietro E. Cippà, Ariana Gaspert, Christoph Etter, Zehra Guenduez, Sylvie Ferrari-Lacraz, Barbara Rüsi, Thomas Fehr,