Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
335115 | Psychiatry Research: Neuroimaging | 2010 | 4 Pages |
Abstract
Frontal systems dysfunction and abandonment fears represent central features of borderline personality disorder (BPD). BPD subjects (n = 10) and matched non-psychiatric comparison subjects (n = 10) completed a social–cognitive task with two confederates instructed to either include or exclude subjects from a circumscribed interaction. Evoked cerebral blood oxygenation in frontal cortex was measured using 16-channel functional near infrared spectroscopy. BPD subjects showed left medial prefrontal cortex hyperactivation during social exclusion suggesting potential dysfunction of frontolimbic circuitry.
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Authors
Anthony C. Ruocco, John D. Medaglia, Jennifer R. Tinker, Hasan Ayaz, Evan M. Forman, Cory F. Newman, J. Michael Williams, Frank G. Hillary, Steven M. Platek, Banu Onaral, Douglas L. Chute,