Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3351975 | Human Immunology | 2011 | 4 Pages |
Abstract
The axiom of human leukocyte incompatibility (HLA) incompatibility has always led scientists to consider cancer transmission between HLA-different individuals impossible. In fact, cancer transmission between individuals represents a frightening possibility in animal populations with limited HLA diversity or for rare cancers exploiting downregulation of HLA expression. We review here evidence from nonhuman models and settings for interhuman transmission.
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Authors
Daniele Focosi, Monica De Donno, Serena Barbuti, Sara Davini, Silvia Fornaciari, Michele Curcio, Maria Luciana Mariotti, Fabrizio Scatena,