Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3352011 | Human Immunology | 2009 | 6 Pages |
Abstract
Human leucocyte antigen–G (HLA-G) is a nonclassical HLA class I molecule observed for the first time in human cytotrophoblast. Several investigations have demonstrated the presence of soluble HLA-G in oocyte/embryo secretome. A focus on the possible role of HLA-G in oocyte/embryo context will be developed in this review. In addition, the possible use of HLA-G in assisted reproductive technology will be treated.
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Authors
Roberta Rizzo, Marina Stignani, Loredana Melchiorri, Olavio R. Baricordi,