| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3352299 | Human Immunology | 2008 | 5 Pages |
Abstract
Recent studies with a humanized anti-CD3 antibody in clinical trials suggested that this drug can induce regulatory CD8+ T cells. In this review, we discuss how these regulatory human CD8+ cells can be generated and the possible molecular tools they may use to inhibit immune responses. We compare our data on CD8+ regulatory cells induced by anti-CD3 stimulation with those reported in other experimental systems to identify both common and unique features of these cells.
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Authors
Vitaly Ablamunits, Kevan C. Herold,