| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3353635 | Immunity | 2008 | 5 Pages |
Abstract
Mitochondrial antiviral immunity involves the detection of viral RNA by intracellular pattern-recognition receptors (PRRs) belonging to the RIG-I-like helicase family. The convergence of these and other signaling molecules to the outer mitochondrial membrane results in the rapid induction of antiviral cytokines including type-1 interferon. Here, we discuss recent studies describing new molecules implicated in the regulation of this antiviral response.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Chris B. Moore, Jenny P-Y. Ting,