Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3355051 | Immunology and Allergy Clinics of North America | 2009 | 13 Pages |
Abstract
Eosinophilic esophagitis is a chronic disease that leads to either persistent symptoms or, at times, intermittent “flares.” It shares many features with other atopic diseases (asthma, allergic rhinitis, and atopic dermatitis), including the following: T helper 2 cells and eosinophils play a critical role in the pathogenesis of the disease; avoidance of allergens promotes remission of disease and symptom control; and locally applied corticosteroids provide control. Finally, most patients who have eosinophilic gastrointestinal disorders have an associated atopic disease.
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Authors
Soma Jyonouchi, Terri A. Brown-Whitehorn, Jonathan M. Spergel,