Article ID Journal Published Year Pages File Type
3355051 Immunology and Allergy Clinics of North America 2009 13 Pages PDF
Abstract

Eosinophilic esophagitis is a chronic disease that leads to either persistent symptoms or, at times, intermittent “flares.” It shares many features with other atopic diseases (asthma, allergic rhinitis, and atopic dermatitis), including the following: T helper 2 cells and eosinophils play a critical role in the pathogenesis of the disease; avoidance of allergens promotes remission of disease and symptom control; and locally applied corticosteroids provide control. Finally, most patients who have eosinophilic gastrointestinal disorders have an associated atopic disease.

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