Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3356214 | Immunology Letters | 2007 | 5 Pages |
Abstract
Mimotopes are epitope-mimicking structures. When applied for immunizations they induce desired antibody specificities exclusively based on the principle of molecular mimicry. This is important as antibodies directed against tumor-associated antigens may harbor diverse biological effects depending on their epitope specificity. Thus they may inhibit or promote tumor growth. This review gives an update on different vaccination strategies based on the mimotope concept.
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Authors
Angelika B. Riemer, Erika Jensen-Jarolim,