Article ID Journal Published Year Pages File Type
3356457 Immunology Letters 2006 8 Pages PDF
Abstract

Antibodies can act like adjuvants. They can potently enhance the antibody response, and in the case of IgG and IgE also the T cell response, to the very antigen they are specific for. In this review we will discuss the recent advances made in our understanding of the underlying mechanisms of antibody-mediated feedback enhancement. The immuno-stimulatory properties of IgM, IgG1, IgG2a, IgG2b, IgG3 and IgE will be reviewed in relationship to the complement system and Fc receptors and the physiological relevance will be discussed.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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