Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3356457 | Immunology Letters | 2006 | 8 Pages |
Abstract
Antibodies can act like adjuvants. They can potently enhance the antibody response, and in the case of IgG and IgE also the T cell response, to the very antigen they are specific for. In this review we will discuss the recent advances made in our understanding of the underlying mechanisms of antibody-mediated feedback enhancement. The immuno-stimulatory properties of IgM, IgG1, IgG2a, IgG2b, IgG3 and IgE will be reviewed in relationship to the complement system and Fc receptors and the physiological relevance will be discussed.
Keywords
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Authors
Andrew Getahun, Birgitta Heyman,