Article ID Journal Published Year Pages File Type
3358344 Inmunología 2008 9 Pages PDF
Abstract
Current phosphoproteomic approaches are a powerful tool for monitoring global molecular responses to the activation or deactivation of signal transduction pathways. Moreover, relevant advances in Proteomics and Mass Spectrometry (MS) technologies have enabled the identification of thousands of known and novel phosphorylation targets. Indeed, today's scientists take heed of those strategies for functional phosphoprofiling studies of signalling pathways, for drug discovery and for the understanding of the etiology of different diseases.
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