| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 335864 | Psychiatry Research: Neuroimaging | 2007 | 4 Pages |
Abstract
Using PET neuroimaging, we demonstrated that four frontotemporal lobar dementia (FTLD) patients had significantly decreased serotonin 5-HT1A binding potential (BP) compared with controls in all 10 brain regions examined. These pilot data suggest that profound 5-HT1A BP losses may be present and contribute to symptomatology and treatment response in FTLD.
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Authors
Krista L. Lanctôt, Nathan Herrmann, Hooman Ganjavi, Sandra E. Black, Pablo M. Rusjan, Sylvain Houle, Alan A. Wilson,