Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3358791 | International Journal of Antimicrobial Agents | 2013 | 4 Pages |
Abstract
Klebsiella pneumoniae carbapenemase (KPC)-type enzymes have largely disseminated worldwide among K. pneumoniae isolates. In this study, 11 non-K. pneumoniae KPC-producing enterobacterial isolates from four hospitals located in different Colombian cities were genetically investigated. All isolates were multidrug-resistant and harboured the blaKPC-2 gene along with several other acquired β-lactamase genes. The blaKPC-2 gene was associated with transposon Tn4401b inserted in different loci of plasmids varying in size and replicon type. The presence of KPC-2 in different enterobacterial species from different cities within Colombia underlines the spread of KPC beyond K. pneumoniae.
Related Topics
Life Sciences
Immunology and Microbiology
Applied Microbiology and Biotechnology
Authors
Gaelle Cuzon, Thierry Naas, Adriana Correa, John P. Quinn, Maria-Virginia Villegas, Patrice Nordmann,