| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3360300 | International Journal of Antimicrobial Agents | 2009 | 4 Pages |
Abstract
Amphotericin B microspheres (M-AMB) are a new, inexpensive formulation of amphotericin B. In this study, we tested the efficacy of this new formulation for treating murine disseminated infections by Candida glabrata or Candida tropicalis. M-AMB showed a similar efficacy to that of amphotericin B deoxycholate and liposomal amphotericin B in the treatment of both disseminated murine infections. Its low toxicity and inexpensive production costs make this formulation potentially attractive for the treatment of fungal infections.
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Authors
Marçal Mariné, Raquel Espada, Juan Torrado, F. Javier Pastor, Josep Guarro,