| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3361341 | International Journal of Antimicrobial Agents | 2007 | 5 Pages |
Abstract
Blastoschizomyces capitatus is an emerging pathogenic fungus that can cause deep invasive diseases in neutropenic patients. We developed a model of disseminated blastoschizomycosis in immunosuppressed mice to evaluate the effectiveness of amphotericin B, flucytosine, fluconazole and voriconazole. High-dose fluconazole was the most effective drug at prolonging the survival of mice and at reducing fungal burden in the kidneys, spleen and liver.
Related Topics
Life Sciences
Immunology and Microbiology
Applied Microbiology and Biotechnology
Authors
Carolina Serena, Marçal Mariné, Rita Marimon, Francisco Javier Pastor, Josep Guarro,