Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3364322 | International Journal of Infectious Diseases | 2010 | 4 Pages |
Abstract
SummaryDisseminated disease caused by non-tuberculous, environmental mycobacteria (EM) reflects impaired host immunity. Disseminated disease caused by Mycobacterium scrofulaceum has primarily been reported in patients with AIDS. Moreover, observing M. scrofulaceum as the agent of localized disease in childhood has become increasingly rare. We report the first case of disseminated disease caused by M. scrofulaceum in a child with inherited interferon-γ receptor 1 (IFN-γR1) complete deficiency. As in this case, mycobacterial bone infections in IFN-γR1 deficiency can sometimes mimic the clinical picture of chronic recurrent multifocal osteomyelitis.
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Authors
Maria Grazia Marazzi, Ariane Chapgier, Anna-Carla Defilippi, Vito Pistoia, Sara Mangini, Cesarina Savioli, Anna Dell’Acqua, Jacqueline Feinberg, Enrico Tortoli, Jean-Laurent Casanova,