| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3368749 | Journal of Clinical Virology | 2016 | 4 Pages |
Abstract
IntroductionAdenoviral infection is a classic cause of lymphohistiocytic hemophagocytosis (LH) in bone marrow transplantation but is rare outside this setting.Case reportA 31-year-old female, with a history of treated mesencephalic astrocytoma, was hospitalized for fever, pancytopenia, elevated liver enzymes, hyperferritinemia and hypertriglyceridemia. Adenovirus viral load in blood was 7.3 × 109 copies/mL. Bone marrow aspirate examination confirmed LH. The patient recovered without specific LH or adenovirus-directed treatment.ConclusionAdenovirus-related LH, common in bone marrow transplant recipients, should also be considered in patients with chemotherapy in solid tumors.
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Authors
G. Mellon, B. Henry, O. Aoun, D. Boutolleau, A. Laparra, J. Mayaux, M. Sanson, E. Caumes,