Improvement of surgical antibiotic prophylaxis: a prospective evaluation of personalized antibiotic kits

SummaryThis prospective study compared personalized surgical antibiotic prophylaxis kits (SAPKs) with freely prescribed antibiotics. SAPKs use significantly enhanced national guidelines on surgical antibiotic prophylaxis application (82% vs 41%, P<0.001), and result in limited errors in terms of antibiotic choice (3% vs 28%, P<0.001), timing of administration (12% vs 24%, P=0.003) and prophylaxis duration (1.5% vs 22%, P<0.001), thereby demonstrating their effectiveness.