Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3374520 | Journal of Infection | 2014 | 9 Pages |
Abstract
Both SCH-PH and IPAH feature plexogenic arteriopathy and increased periarterial T cell and mast cell density. SCH-PH and IPAH differ only with respect to the density of dendritic CD83+ cells. These findings imply ongoing antigenic stimulation in SCH-PH, yet a pattern of pulmonary vasculopathy similar to IPAH, suggestive of a final common pathway in their pathogenesis of PAH.
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Authors
Thais Mauad, Geanette Pozzan, Tatiana Lanças, Maria J. Overbeek, Rogério Souza, Carlos Jardim, Marisa Dolhnikoff, George Mello, Ruy Camargo Pires-Neto, Fabiola del Carlo Bernardi, Katrien Grünberg,