Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3375337 | Journal of Infection | 2011 | 4 Pages |
Abstract
SummaryInfectious diarrhea is a common occurrence in the immunosuppressed population. We present a 43-year-old individual with large-volume stool output Norovirus acute gastroenteritis in the setting of relapsed refractory acute myelogenous leukemia, hematopoietic stem cell transplantation, and biopsy-proven cutaneous and pulmonary graft-versus-host disease. Therapeutic options such as intravenous immunoglobulin or reduction of immunosuppressants were not a feasible choice. A prompt clinical cure was achieved with nitazoxanide, a broad-spectrum antimicrobial agent. Nitazoxanide may be a safe therapeutic alternative, in which a reduction in immunosuppression may not be a viable option.
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Authors
Danish M. Siddiq, Hoonmo L. Koo, Javier A. Adachi, George M. Viola,