Article ID Journal Published Year Pages File Type
3376438 Journal of Infection 2006 4 Pages PDF
Abstract

SummaryPatients with mutations in the IFNγ/IL-12 pathway show an exquisite susceptibility to mycobacterial diseases. An IL-12Rβ1 deficient patient with impaired intestinal absorption suffered from a 13 year culture-positive Mycobacterium bovis-BCG infection with acquired multidrug resistance. A combined parenteral and enteral anti-mycobacterial treatment, including recombinant IFNγ, helped to clear his infection.

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Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
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