Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3376549 | Journal of Infection | 2007 | 4 Pages |
Abstract
This is the first report to describe an apparently healthy girl, who developed recurrent occult bacteremia by the same Streptococcus pneumoniae strain, at 11 and 15Â months of age. The two separately isolated organisms were demonstrated to have the identical serotype (type 6B), antibiotic susceptibility (intermediately penicillin-resistant), genotypes of penicillin-binding proteins, and patterns of pulse-field gel electrophoresis. The serum levels of anti-type 6B antibodies showed poor responses after both bacteremic episodes, but other immunological workups did not demonstrate any abnormalities. This case indicates that occult bacteremia may recur due to an identical pneumococcal strain in an immunocompetent infant, and that early introduction of pneumococcal conjugate vaccine is necessary in Japan.
Related Topics
Life Sciences
Immunology and Microbiology
Applied Microbiology and Biotechnology
Authors
Kousaku Matsubara, Takashi Fukaya, Kimiko Ubukata, Meng Chen, Hiroyuki Nigami, Hidekazu Harigaya, Hideo Nozaki, Takayuki Tanaka,