Invasive Brevundimonas vesicularis bacteremia: Two case reports and review of the literature

There are few reports of invasive infections caused by Brevundimonas vesicularis. We report two cases of B. vesicularis bacteremia confirmed by culture and 16S rRNA sequence analysis with highly variable sensitivity to broad-spectrum antibiotics. Initial empiric therapy with anti-pseudomonal antibiotics plus trimethoprim-sulfamethoxazole for hospital-acquired B. vesicularis infections should be considered.