Clinical metamorphosis of hand, foot and mouth disease (HFMD)

HFMD is an acute viral exanthematous disorder of early childhood. Characterized by erythematous papulovesicular eruptions around mouth, on palms, soles, and buttocks, syndrome is caused by eleven types of enteroviruses; Coxsackie A16 is by far the commonest one. Generally a mild and self recoverable disease some of the recent outbreaks have reported serious neurological complications mainly when Enterovirus 71 is the causative agent. Onychomadesis, a noninflammatory nail dystrophy is lately discovered finding associated with HFMD.