| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3383400 | Reumatología Clínica | 2011 | 4 Pages |
Abstract
Bone tissue is constantly renewed by the coordinated action of osteoclasts and osteoblasts. Osteocytes have a prominent role in the onset of bone remodeling at selected sites of the skeleton. These and other osteoblastic cells produce a variety of mediators that modulate the differentiation of osteoclast precursors, a critical step for bone resorption to occur. Among them, M-CSF and RANKL are especially important.
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Authors
José A. Riancho, Jesús Delgado-Calle,