Daño en pacientes cubanos con lupus eritematoso sistémico. Relación con características de la enfermedad

We found that 39 patients (48,8%) had some degree of damage. More involved domains were the musculoskeletal (18,8%), neuropsychiatric, and skin, 16,3%, pulmonary and ocular, present in 15% of cases. In the multivariate analysis, damage was associated with the use of higher than 30 mg/day Prednisone doses for more of 4 weeks (OR=54,68, CI 95%=3,56-97,45, p=0.001), presence of leukopenia (RO=18,73, CI 95%=2,74-62,23 m p=0,004), and time course of disease (OR=1,02, CI 95%=1,00 2-1,09, p=0.006). Conclusions: Damage was practically present in half of the study patients, the most involved domain was the musculoskeletal, and use of higher than 30 mg prednisone doses were the factor most associated with the presence of damage.