Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3384000 | Reumatología Clínica | 2006 | 8 Pages |
Abstract
HA is involved in many mechanisms of action ranging from interaction with mechanosensitive articular pain receptors to its ability to modulate extracellular matrix homeostasis. Although low molecular weight HA has a better safety profile and is slightly superior in in vitro studies and animal experimentation, clinical trials evaluating the efficacy of the drug show insufficient evidence to enable one type of HA to be recommended in preference to any other.
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Authors
J. Monfort, P. Benito,